Helicobacter pylorigenetic diversification in the Mongolian gerbil model

Placental Development in the Mongolian Gerbil

Early gerbil development was studied from days 4 through 12 of gestation. Implantation occurs on day 8 in a shallow antimesometrial implantation crypt. The proamniotic cavity forms from an invagination of basal trophoblast and a folding together of the rim of the cup thus produced. The approximation of this rim gives rise to the ectoplacental cone. The further development and expansion of the e...

Helicobacter pylori Infection Enhances W-Methyl-./V-nitrosourea-induced Stomach Carcinogenesis in the Mongolian Gerbil

No previous report has demonstrated the relationship between Helico bacter pylori (HP) infection and gastric carcinogenesis in an experimental animal model. A total of 170 male Mongolian gerbils (MGs) were divided into nine groups (18 S n S 20 for each group). MGs of four groups were inoculated with HP before or after continuous A'-methyl-A'-nitrosourea (MNU) administration via the drinking wat...

Angiotensin II receptor expression and relation to Helicobacter pylori-infection in stomach of the Mongolian gerbil

Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogenesis in the Mongolian gerbil.

No previous report has demonstrated the relationship between Helicobacter pylori (HP) infection and gastric carcinogenesis in an experimental animal model. A total of 170 male Mongolian gerbils (MGs) were divided into nine groups (18 < or = n < or = 20 for each group). MGs of four groups were inoculated with HP before or after continuous N-methyl-N-nitrosourea (MNU) administration via the drink...

Virulence Factors of Helicobacter pylori Responsible for Gastric Diseases in Mongolian Gerbil

Helicobacter pylori infection induces various gastroduodenal diseases. We examined the role of two genes, vacA and cagE, in the gastric pathogenesis induced by H. pylori using a long-term (62 wk) animal model. Reportedly, both genes are associated with the virulence of H. pylori: vacA encodes vacuolating cytotoxin, and cagE, with other genes in the cag pathogenicity islands, encodes a type IV s...